Thermo Fisher Scientific PPP1R7 Polyclonal Antibody
Rabbit polyclonal antibody targeting human PPP1R7 protein; validated for WB and ICC/IF applications; detects endogenous PPP1R7; affinity-purified and supplied as liquid form; suitable for research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PPP1R7 (Accession Q15435), corresponding to amino acid residues E290–R340 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854376 |
Product Specific Information
Antibody detects endogenous levels of total PPP1R7.
Target Information
In eukaryotes, phosphorylation and dephosphorylation of proteins on serine and threonine residues regulate diverse cellular functions such as division, homeostasis, and apoptosis. Protein phosphatases play a central role in these processes. The protein phosphatase 1 (PP1) holoenzyme is typically a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit.
Sds22, also known as PPP1R7 (protein phosphatase 1, regulatory subunit 7), is a 360-amino-acid nuclear protein containing ten LRR (leucine-rich) repeats. It is expressed in various tissues and functions as a regulatory subunit of the PP1 complex, suggesting a role in protein regulation throughout the cell. Multiple isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-106708_PPP1R7_Q15435-1_Rabbit.svg, PA5-106708_PPP1R7_Q15435-1_Rabbit_PDP.jpeg)
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