Thermo Fisher Scientific Tyrosinase Recombinant Rabbit Monoclonal Antibody (6F1B4)
Recombinant rabbit monoclonal antibody specific for human Tyrosinase. Validated for IHC (Paraffin) and ELISA. High purity (Protein A), liquid form, unconjugated. Ideal for melanin biosynthesis and pigmentation research. For research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6F1B4 |
| Immunogen | Synthetic peptide corresponding to amino acids 200–300 of human Tyrosinase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
FAHEAPAFLP WHRLFLLRWE QEIQKLTGDE NFTIPYWDWR DAEKCDICTD EYMGGQHPTN PNLLSPASFF SSWQIVCSRL EEYNSHQSLC NGTPEGPLRR N
Target Information
The enzyme encoded by this gene catalyzes the first two steps, and at least one subsequent step, in the conversion of tyrosine to melanin. It exhibits both tyrosine hydroxylase and dopa oxidase catalytic activities and requires copper for function. Mutations in this gene cause oculocutaneous albinism, while nonpathologic polymorphisms contribute to skin pigmentation variation. The human genome also contains a pseudogene similar to the 3′ half of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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