
Thermo Fisher Scientific mGluR3 (extracellular) Polyclonal Antibody
mGluR3 (extracellular) 폴리클로날 항체로 마우스 및 랫트 시료에 반응. Western blot, IHC(F), ICC/IF 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제된 고순도 항체. PBS 기반 저장용액, -20°C 보관. 연구용 전용 제품.
- 카탈로그번호
- AGC-012-xxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific mGluR3 (extracellular) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:600 |
| Immunohistochemistry (Frozen) (IHC(F)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)GDHNFMRREIKIEGD, corresponding to amino acids 24–38 of rat mGluR3, Extracellular, N-terminus |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size.
- The antibody ships as a lyophilized powder at room temperature.
- Upon arrival, store at -20°C.
- Reconstituted solution can be stored at 4°C for up to 1 week.
- For longer storage, aliquot and store at -20°C.
- Avoid multiple freeze-thaw cycles.
- Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
Glutamate is the main excitatory neurotransmitter in the brain. Initially known to act on ligand-gated receptor channels (NMDA, AMPA, kainate) involved in fast excitatory synaptic transmission, glutamate is now recognized to regulate second messenger-producing enzymes via G-protein-coupled receptors, termed metabotropic glutamate receptors (mGluRs).
Group-I receptors (mGluR1a, mGluR5) stimulate phospholipase C, increasing phosphoinositide turnover and calcium release.
Group-II and Group-III receptors (including mGluR2 and mGluR3) inhibit adenylyl cyclase activity.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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