Thermo Fisher Scientific COX1 Recombinant Rabbit Monoclonal Antibody (6B6)
COX1 단백질을 표적하는 재조합 토끼 단클론 항체로 Western Blot 및 유세포분석에 적합. 인간 및 생쥐 반응성. 고순도 친화 크로마토그래피 정제. 안정적인 액상 형태로 -20°C 이하 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:5,000
Flow Cytometry (Flow)
- Tested Dilution: 1:20–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6B6 |
| Immunogen | A synthesized peptide derived from human COX1 (aa 126–140) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.33 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898306 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
PTGS1 (COX1, Cyclooxygenase 1) is the key enzyme in prostaglandin biosynthesis and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution.
This gene encodes PTGS1, which regulates angiogenesis in endothelial cells and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis.
Alternative splicing of this gene generates two transcript variants, whose expression is differentially regulated by cytokines and growth factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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