Thermo Fisher Scientific COX1 Recombinant Rabbit Monoclonal Antibody (6B6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:5,000

-

Flow Cytometry (Flow)

1:20-1:200

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

6B6

Immunogen

A synthesized peptide derived from human COX1 (aa 126-140). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:COX1,uniProtId:P23219-1,ncbiNodeId:9606,antigenRange:126-140,antigenLength:599,antigenImageFileName:MA5-38392_COX1_P23219-1_Rabbit.svg,antigenImageFileNamePDP:MA5-38392_COX1_P23219-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol, 150mM NaCl

Contains

0.02% sodium azide

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Wet ice

RRID

AB_2898306

Product Specific Information

This antibody has been tested in direct-ELISA

Target Information

PTGS1 (COX1, Cyclooxygenase 1) is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.