Thermo Fisher Scientific TCP-1 beta Polyclonal Antibody
Rabbit polyclonal antibody recognizing human TCP-1 beta. Validated for WB and IHC(P). Supplied as liquid, unconjugated form, purified by antigen affinity chromatography. Suitable for research use only, stored at -20°C.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Chaperonin Containing TCP1, Subunit 2 (amino acids 1–488 of the target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903519 |
Target Information
TCP-1 beta is a molecular chaperone that is part of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The CCT complex assists in folding various proteins, including actin and tubulin. Alternate transcriptional splice variants of the TCP-1 beta gene have been observed but not thoroughly characterized. Dysfunction of the TCP-1 beta protein has been associated with epididymo-orchitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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