Thermo Fisher Scientific Chemerin Polyclonal Antibody
Chemerin 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. -20°C 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Chemerin (amino acid range 21–155 of the target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903520 |
Target Information
Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs).
Tazarotene-induced gene (TIG) proteins, also designated retinoic acid receptor responder proteins or RAR-responsive proteins, can be membrane bound or secreted.
TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles, and endothelial cells as well as in pancreas, spleen, and intestine.
TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids.
TIG2 is a secreted protein mainly expressed in epidermis, hair follicles, and endothelial cells. TIG2 is inhibited in psoriatic lesions and activated by tazarotene in skin rafts and epidermis of psoriatic lesions.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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