Thermo Fisher Scientific CD4 Monoclonal Antibody (MIL17), FITC

Applications

• Flow Cytometry (Flow): Neat
• Publications: View 1 publication

Product Specifications

Additional Formats

• Unconjugated
• PE
• Request custom conjugation

Product Specific Information

For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.

Target Information

The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV.
CD4 is primarily expressed in T helper cells, but also in monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 expression is found in thymus, lymph nodes, tonsils, spleen, and in specific regions of the brain and gut.
CD4 functions to initiate or augment early T-cell activation via its association with the T-cell receptor complex and Lck kinase.
It may also mediate neuronal damage in infectious and immune-mediated CNS diseases.
Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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