Thermo Fisher Scientific CD4 Monoclonal Antibody (MIL17), PE

Applications

• Flow Cytometry (Flow)

Tested Dilution: Neat

Product Specifications

Additional Formats

• Unconjugated (MA5-28363)
• FITC (MA5-16854)
• Request custom conjugation

Product Specific Information

• Reconstitute with 1 mL of distilled water.
• After reconstitution, store product undiluted at 4ºC in the dark.
• For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.

Target Information

The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes (T helper cells) and may also be expressed by monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 expression is found in thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut.
CD4 functions to initiate or augment early T-cell activation through association with the T-cell receptor complex and protein tyrosine kinase Lck. It may also mediate neuronal damage in infectious and immune-mediated CNS diseases.
Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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