Thermo Fisher Scientific LMAN1 Monoclonal Antibody (OTI1E3), TrueMAB
LMAN1 단백질을 인식하는 Mouse monoclonal antibody로, Western blot, IHC, ICC/IF, Flow Cytometry에 적합합니다. Human 및 Dog 시료에 반응하며, 고순도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E3 |
| Immunogen | Full-length human recombinant LMAN1 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.24 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by the LMAN1 gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi apparatus, recycling between these compartments. It functions as a mannose-specific lectin and belongs to a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in this gene are associated with a coagulation defect, specifically combined factor V-factor VIII deficiency, a rare autosomal recessive disorder characterized by reduced levels of both coagulation factors V and VIII.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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