Thermo Fisher Scientific LMAN1 Monoclonal Antibody (OTI1A8), TrueMAB
LMAN1 단백질을 인식하는 Mouse monoclonal antibody로, WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. Human, Dog, Rat 반응성. Affinity chromatography로 정제된 1 mg/mL 액상 시약으로, PBS/BSA/glycerol buffer에 보존. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:500 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A8 |
| Immunogen | Full length human recombinant protein of human LMAN1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and belongs to a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in this gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene responsible for combined factor V-factor VIII deficiency, a rare autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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