Thermo Fisher Scientific LMAN1 Monoclonal Antibody (OTI1A8), TrueMAB

Applications and Tested Dilution

Product Specifications

Target Information

The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and belongs to a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in this gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene responsible for combined factor V-factor VIII deficiency, a rare autosomal recessive disorder in which both coagulation factors V and VIII are diminished.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.