Thermo Fisher Scientific SQSTM1 Monoclonal Antibody (OTI4G9), TrueMAB
Human SQSTM1 단백질을 인식하는 Mouse monoclonal antibody (clone OTI4G9). Western blot, IHC, Flow cytometry에 적합하며, 고순도의 액상 형태로 제공. NF-κB 신호전달 관련 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G9 |
| Immunogen | Full length human recombinant protein of human SQSTM1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The SQSTM1 gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-κB) signaling pathway.
This protein acts as a scaffolding/adaptor molecule in cooperation with TNF receptor-associated factor 6 to mediate NF-κB activation in response to upstream signals.
Alternatively spliced transcript variants encoding identical or distinct isoforms have been identified.
Mutations in this gene are associated with sporadic and familial Paget disease of bone.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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