Thermo Fisher Scientific MAK10 Polyclonal Antibody
Thermo Fisher Scientific의 MAK10 폴리클로날 항체는 인간 단백질에 특이적으로 반응하며 Western blot 및 IHC(P) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제된 고순도 항체로, 액상 형태이며 장기 보관 시 -20°C에서 안정적으로 저장 가능합니다.
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Thermo Fisher Scientific MAK10 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MAK10. Recombinant protein control fragment (Product #RP-92956). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643702 |
Product Specific Information
Immunogen sequence:
KKVRPLSREI TMSQAYQNMC AGMFKTMVAF DMDGKVRKPK FELDSEQVRY EHRFAPFNSV MTPPPVHYLQ FKEMSDLNKY SPPPQSPELY VAASKHFQQ
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 98%
Target Information
The MAK10 gene encodes a 733-amino acid protein with several regions of similarity to T cell receptor alpha-subunit V regions in yeast. The mammalian homologue of yeast MAK10 (also known as EGAP) is a subunit of a conserved N-terminal acetyltransferase (NAT) complex among vertebrates.
It is expressed broadly in developing rat embryos but becomes restricted in adults, remaining detectable mainly in tissues undergoing continuous renewal or responding to injury.
The MAK10-NAT complex regulates proteins essential for embryonic growth and vessel development and co-assembles in mammalian cells to control proliferation and TOR signaling.
At least two isoforms of MAK10 are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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