Thermo Fisher Scientific MEKK2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MEKK2. Recombinant protein control fragment (Product #RP-102059). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MEKK2,uniProtId:Q9Y2U5-1,ncbiNodeId:9606,antigenRange:74-200,antigenLength:619,antigenImageFileName:PA5-54443_MEKK2_Q9Y2U5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54443_MEKK2_Q9Y2U5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.8 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643867

Product Specific Information

Immunogen sequence: IAFGQSMDLH YTNNELVIPL TTQDDLDKAV ELLDRSIHMK SLKILLVING STQATNLEPL PSLEDLDNTV FGAERKKRLS IIGPTSRDRS SPPPGYIPDE LHQVARNGSF TSINSEGEFI PESMDQM

Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.

Target Information

MAP3K2 (MEKK2) is a serine/threonine kinase that activates kinases involved in the MAP kinase signaling pathway. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.