Thermo Fisher Scientific MEKK2 Polyclonal Antibody
Human MEKK2 단백질에 특이적인 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제된 고품질 항체. 장기 보관 시 -20°C에서 안정적 저장.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MEKK2. Recombinant protein control fragment (Product #RP-102059). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643867 |
Product Specific Information
Immunogen sequence:
IAFGQSMDLH YTNNELVIPL TTQDDLDKAV ELLDRSIHMK SLKILLVING STQATNLEPL PSLEDLDNTV FGAERKKRLS IIGPTSRDRS SPPPGYIPDE LHQVARNGSF TSINSEGEFI PESMDQM
Highest antigen sequence identity to the following orthologs:
- Mouse: 91%
- Rat: 91%
Target Information
MAP3K2 (MEKK2) is a serine/threonine kinase that activates kinases involved in the MAP kinase signaling pathway. This kinase directly phosphorylates and activates Ikappa B kinases, playing a role in NF-kappa B signaling. It also binds and activates protein kinase C-related kinase 2, suggesting involvement in regulated signaling processes.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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