Thermo Fisher Scientific SCRN2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 176-425 of human SCRN2 (NP_6123642) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SCRN2,uniProtId:Q96FV2-1,ncbiNodeId:9606,antigenRange:176-425,antigenLength:425,antigenImageFileName:PA5-88321_SCRN2_Q96FV2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88321_SCRN2_Q96FV2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.27 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804827

Product Specific Information

Immunogen sequence: GRLWAAQRIQ EGARNISNQL SIGTDISAQH PELRTHAQAK GWWDGQGAFD FAQIFSLTQQ PVRMEAAKAR FQAGRELLRQ RQGGITAEVM MGILRDKESG ICMDSGGFRT TASMVSVLPQ DPTQPCVHFL TATPDPSRSV FKPFIFGMGV AQAPQVLSPT FGAQDPVRTL PRFQTQVDRR HTLYRGHQAA LGLMERDQDR GQQLQQKQQD LEQEGLEATQ GLLAGEWAPP LWELGSLFQA FVKRESQAYA; Positive Samples: BxPC-3, HeLa, A-375, Mouse liver, Mouse kidney, Mouse intestine

Target Information

SCRN2 is a member of the secernin family of proteins which includes the homologous SCRN1, a protein that was first identified as being involved in the regulation of exocytosis from peritoneal mast cells. Little is known of SCRN2, but studies have shown that SCRN1 may possess epitopes that function as tumor-associated antigens in gastric cancers and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN2 may also be involved in protein secretion or the regulation of cell growth.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.