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Thermo Fisher Scientific Topoisomerase I, Mitochondrial (TOP1MT) Recombinant Rabbit Monoclonal Antibody (TOP1MT, 2883R)
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미토콘드리아 DNA 토포이소머라제 I(TOP1MT)을 인식하는 토끼 단클론 항체. 포르말린 고정 조직의 IHC(P) 검증 완료. HEK293 발현 리콤비넌트 항체로 높은 특이성과 재현성 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- 116447-RBM4-P0
- 판매단위
- pk
카탈로그
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마지막 업데이트 2025. 07. 31. 오전 03:45
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Thermo Fisher Scientific 116447-RBM4-P0 Topoisomerase I, Mitochondrial (TOP1MT) Recombinant Rabbit Monoclonal Antibody (TOP1MT, 2883R) 20 ug pk판매 단위 pk ·
재고 확인 필요
443,800원VAT 포함 488,180원
Thermo Fisher Scientific · Thermo Fisher Scientific Topoisomerase I, Mitochondrial (TOP1MT) Recombinant Rabbit Monoclonal Antibody (TOP1MT, 2883R)
Applications
Tested Application and Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | TOP1MT, 2883R |
| Immunogen | Recombinant full-length human TOP1MT protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For immunohistochemistry (PFA-fixed samples):
Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
This gene encodes a mitochondrial DNA topoisomerase that modifies DNA topology. The encoded protein is a type IB topoisomerase that catalyzes transient breaking and rejoining of DNA strands to relieve tension and supercoiling generated during mitochondrial DNA replication and transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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