Thermo Fisher Scientific Phospho-Cytokeratin 20 (Ser13) Polyclonal Antibody
Phospho-Cytokeratin 20 (Ser13) 특이적 폴리클로날 항체로, 인산화된 Ser13 부위에서만 내인성 Cytokeratin 20을 검출합니다. Western blot 및 파라핀 절편 면역조직화학(IHC) 분석에 적합하며, 1 mg/mL 농도의 액상 형태로 제공됩니다. -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KRT20 (Accession P35900), corresponding to amino acid residues around phosphorylated Ser13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816080 |
Product Specific Information
Antibody detects endogenous levels of Cytokeratin 20 only when phosphorylated at Ser13.
Target Information
The protein encoded by this gene is a member of the keratin family. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins.
Type I cytokeratins consist of acidic proteins arranged in pairs of heterotypic keratin chains. Cytokeratin 20 is a major cellular protein of mature enterocytes and goblet cells, specifically expressed in the gastric and intestinal mucosa.
Type I cytokeratin genes are clustered in a region of chromosome 17q12–q21.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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