Thermo Fisher Scientific BAG2 Recombinant Rabbit Monoclonal Antibody (6D6Z0)
BAG2 단백질을 인식하는 Rabbit Recombinant Monoclonal Antibody (Clone 6D6Z0). Western blot, IHC, ELISA에 적합. Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제, 안정적 PBS 기반 저장용액 포함.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6D6Z0 |
| Immunogen | A synthetic peptide corresponding to amino acids 1–100 of human BAG2 (O95816) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.34 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS (pH 7.3), with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912035 |
Product Specific Information
- Positive test controls: A-549, PC-3, Jurkat
- Immunogen sequence:
MAQAKINAKA NEGRFCRSSS MADRSSRLLE SLDQLELRVE ALREAATAVE QEKEILLEMI HSIQNSQDMR QISDGEREEL NLTANRLMGR TLTVEVSVET
Target Information
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All BAG proteins contain an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein has 211 amino acids. BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain both in vitro and in mammalian cells. All three proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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