Thermo Fisher Scientific GluR3 Polyclonal Antibody
GluR3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot과 ELISA에 적합합니다. 인간 및 생쥐 시료에 반응하며, 세포막 및 시냅스 위치 단백질 검출에 유용합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 200–490 of human GRIA3 (NP_0008193) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.36 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804700 |
Product Specific Information
- Positive Samples: U-251MG, PC-3, Mouse brain, Mouse lung
- Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse
Immunogen sequence:
QEFRRIIEEM DRRQEKRYLI DCEVERINTI LEQVVILGKH SRGYHYMLAN LGFTDILLER VMHGGANITG FQIVNNENPM VQQFIQRWVR LDEREFPEAK NAPLKYTSAL THDAILVIAE AFRYLRRQRV DVSRRGSAGD CLANPAVPWS QGIDIERALK MVQVQGMTGN IQFDTYGRRT NYTIDVYEMK VSGSRKAGYW NEYERFVPFS DQQISNDSAS SENRTIVVTT ILESPYVMYK KNHEQLEGNE RYEGYCVDLA YEIAKHVRIK YKLSIVGDGK YGARDPETKI W
Target Information
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits forming ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors and is subject to RNA editing (AGA→GGA; R→G). Alternative splicing at this locus results in different isoforms with varying signal transduction properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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