Thermo Fisher Scientific GluR3 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Positive Samples: U-251MG, PC-3, Mouse brain, Mouse lung
• Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse

Immunogen sequence:
QEFRRIIEEM DRRQEKRYLI DCEVERINTI LEQVVILGKH SRGYHYMLAN LGFTDILLER VMHGGANITG FQIVNNENPM VQQFIQRWVR LDEREFPEAK NAPLKYTSAL THDAILVIAE AFRYLRRQRV DVSRRGSAGD CLANPAVPWS QGIDIERALK MVQVQGMTGN IQFDTYGRRT NYTIDVYEMK VSGSRKAGYW NEYERFVPFS DQQISNDSAS SENRTIVVTT ILESPYVMYK KNHEQLEGNE RYEGYCVDLA YEIAKHVRIK YKLSIVGDGK YGARDPETKI W

Target Information

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits forming ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors and is subject to RNA editing (AGA→GGA; R→G). Alternative splicing at this locus results in different isoforms with varying signal transduction properties.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.