Thermo Fisher Scientific GluR3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 200-490 of human GRIA3 (NP_0008193) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GluR3,uniProtId:P42263-1,ncbiNodeId:9606,antigenRange:200-490,antigenLength:894,antigenImageFileName:PA5-88158_GluR3_P42263-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88158_GluR3_P42263-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.36 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804700

Product Specific Information

Positive Samples: U-251MG, PC-3, Mouse brain, Mouse lung; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse

Immunogen sequence: QEFRRIIEEM DRRQEKRYLI DCEVERINTI LEQVVILGKH SRGYHYMLAN LGFTDILLER VMHGGANITG FQIVNNENPM VQQFIQRWVR LDEREFPEAK NAPLKYTSAL THDAILVIAE AFRYLRRQRV DVSRRGSAGD CLANPAVPWS QGIDIERALK MVQVQGMTGN IQFDTYGRRT NYTIDVYEMK VSGSRKAGYW NEYERFVPFS DQQISNDSAS SENRTIVVTT ILESPYVMYK KNHEQLEGNE RYEGYCVDLA YEIAKHVRIK YKLSIVGDGK YGARDPETKI W

Target Information

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.