Thermo Fisher Scientific ICT1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 30-206 of human ICT1 (NP_0015361) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ICT1,uniProtId:Q14197-1,ncbiNodeId:9606,antigenRange:30-206,antigenLength:206,antigenImageFileName:PA5-88159_ICT1_Q14197-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88159_ICT1_Q14197-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.23 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804701

Product Specific Information

Immunogen sequence: LHKQKDGTEF KSIYSLDKLY PESQGSDTAW RVPNGAKQAD SDIPLDRLTI SYCRSSGPGG QNVNKVNSKA EVRFHLATAE WIAEPVRQKI AITHKNKINR LGELILTSES SRYQFRNLAD CLQKIRDMIT EASQTPKEPT KEDVKLHRIR IENMNRERLR QKRIHSAVKT SRRVDMD; Positive Samples: Raji, HT-29, 293T, B-cell, Skov3, Mouse lung, Mouse kidney, Mouse brain; Cellular Location: Mitochondrion

Target Information

Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.