Thermo Fisher Scientific SLC6A8 Polyclonal Antibody
SLC6A8 단백질을 인식하는 염소 유래 다클론 항체로, Western blot 및 IHC(P) 실험에 적합. 인간과 생쥐에 반응하며, 예측 반응종에는 쥐·개·돼지·소 포함. 액상 형태로 제공되며, 안정적 보관을 위해 -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence ASLANLTCDQLADRR, from the internal region of SLC6A8 (aa 193–207) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2554496 |
Product Specific Information
- Predicted to react with human, rat, dog, pig, and cow based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
SLC6A8 (solute carrier family 6 member 8), also known as CT1 (creatine transporter 1), CRT, or CRTR, is a 635 amino acid multi-pass plasma membrane protein belonging to the sodium/neurotransmitter (SNF) family.
It is expressed in various tissues including kidney, skeletal muscle, heart, brain, prostate, testis, and colon.
SLC6A8 functions to transport creatine into and out of cells, particularly in brain and muscle tissue.
Creatine is essential for supplying energy for proper muscle and nerve function.
Defects in the SLC6A8 gene lead to cerebral creatine deficiency, causing X-linked creatine deficiency syndrome characterized by facial anomalies, seizures, and mental retardation.
Multiple isoforms of SLC6A8 exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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