Thermo Fisher Scientific SIM1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1-3 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide with sequence C-SGDRYRTEQYQS, from the internal region of SIM1 (aa 545-557). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SIM1,uniProtId:P81133-1,ncbiNodeId:9606,antigenRange:545-557,antigenLength:766,antigenImageFileName:PA5-37887_SIM1_P81133-1_Goat.svg,antigenImageFileNamePDP:PA5-37887_SIM1_P81133-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2554495

Product Specific Information

This antibody is predicted to react with mouse, rat, dog, pig and cow based on sequence homology.

This antibody is tested in Peptide ELISA: antibody detection limit dilution 2,000.

Target Information

SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis, it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.