Thermo Fisher Scientific RRAD Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.5–2 µg/mL
• Publications: View 1 publication

ChIP assay (ChIP)

• Tested Dilution: –
• Publications: View 1 publication

Product Specifications

Product Specific Information

This antibody is predicted to react with human, rat, dog, pig, and cow based on sequence homology.
Tested in Peptide ELISA with an antibody detection limit dilution of 64,000.

Target Information

The Ras-encoded family of proteins bind GDP and GTP with high affinity and possess low intrinsic GTPase activity, which increases over 100-fold when interacting with cytosolic GTPase activating protein (GAP).
Ras family members include H-Ras, K-Ras, N-Ras, M-Ras, R-Ras, ERas, Rheb, TC21, RASL11B, and Rad (Ras associated with diabetes) GTPase.
Rad GTPase is similar to Ras but lacks typical prenylation motifs at its C terminus. It binds calmodulin, inhibits vascular lesion formation, and has low intrinsic GTPase activity that cannot be stimulated by known GAP molecules.
Rad GTPase is expressed in skeletal muscle, cardiac muscle, and lung tissues, and is overexpressed in skeletal muscle of individuals with type II diabetes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일: PA5-37885_RRAD_O88667-1_Goat_PDP.jpeg, PA5-37885_RRAD_O88667-1_Goat.svg)