Thermo Fisher Scientific NR0B1 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) [IHC (P)]

• Tested Dilution: 10 µg/mL

ELISA

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

• Percent identity with other species by BLAST analysis:
  Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Marmoset (100%); Monkey (94%)
• For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer.
  After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Target Information

This gene encodes a protein that contains a DNA-binding domain.
The encoded protein acts as a dominant-negative regulator of transcription mediated by the retinoic acid receptor.
It also functions as an anti-testis gene by acting antagonistically to Sry.
Mutations in this gene result in X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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