Thermo Fisher Scientific GluR4 Polyclonal Antibody
GluR4 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P) 등 다양한 응용에 적합. 인간과 마우스 반응성 확인됨. 고순도 Protein A 및 항원 친화 크로마토그래피로 정제. 신경전달 관련 연구용으로 최적화된 고품질 항체.
- 카탈로그번호
- PA524217
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | View publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 259–287 amino acids from the central region of human GRIA4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2541717 |
Product Specific Information
This antibody is predicted to react with non-human primate and rat based on sequence homology.
Target Information
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development, and neurodegeneration.
Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels.
Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7.
The kainate/AMPA receptors are primarily responsible for fast excitatory neurotransmission by glutamate, whereas NMDA receptors are characterized by slow kinetics and high Ca²⁺ permeability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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