Thermo Fisher Scientific CHRNA7 Monoclonal Antibody (7F10G1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:1,000

-

Flow Cytometry (Flow)

1:200-1:400

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human

Published species

Mouse

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

7F10G1

Immunogen

Purified recombinant fragment of human CHRNA7 (AA: extra 52-259) expressed in E. coli. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CHRNA7,uniProtId:P36544-1,ncbiNodeId:9606,antigenRange:52-259,antigenLength:502,antigenImageFileName:MA5-31691_CHRNA7_P36544-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31691_CHRNA7_P36544-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2787315

Product Specific Information

MA5-31691 has been tested in indirect ELISA.

Target Information

Chromosome 15 encodes over 700 genes and comprises nearly 3% of the human genome. CHRFAM7A, a fusion protein comprised of FAM7A and AChR alpha7, is encoded by the CHRFAM7A gene, which is located on a region of human chromosome 15 that is associated with several neuropsychiatric disorders, such as schizophrenia and bipolar affective disorder. CHRFAM7A, also known as D-10 or CHRNA7, is a 412 amino acid multi-pass membrane protein that belongs to the nicotinic acetylcholine receptor (nAChR) subfamily of ligand-gated ion channel proteins, a protein superfamily that mediates signal transmission at synapses. CHRFAM7A is expressed in the hippocampus. Alternative splicing of the CHRFAM7A gene produces two splice variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.