Thermo Fisher Scientific CHRNA7 Monoclonal Antibody (7F10G1)
CHRNA7 단백질을 인식하는 Thermo Fisher Scientific의 단일클론 항체로, WB, IHC, Flow, ELISA 등 다양한 응용에 사용 가능. 인간 반응성, Mouse IgG1 형식, Protein G 정제, 1 mg/mL 농도. 신경 관련 연구 및 CHRNA7 기능 분석에 적합.
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Thermo Fisher Scientific CHRNA7 Monoclonal Antibody (7F10G1)
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | - |
| Flow Cytometry (Flow) | 1:200–1:400 | - |
| ELISA | 1:10,000 | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7F10G1 |
| Immunogen | Purified recombinant fragment of human CHRNA7 (AA: extra 52–259) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787315 |
Product Specific Information
MA5-31691 has been tested in indirect ELISA.
Target Information
Chromosome 15 encodes over 700 genes and comprises nearly 3% of the human genome.
CHRFAM7A, a fusion protein comprised of FAM7A and AChR alpha7, is encoded by the CHRFAM7A gene, located on a region of human chromosome 15 associated with several neuropsychiatric disorders such as schizophrenia and bipolar affective disorder.
CHRFAM7A (also known as D-10 or CHRNA7) is a 412 amino acid multi-pass membrane protein belonging to the nicotinic acetylcholine receptor (nAChR) subfamily of ligand-gated ion channel proteins, mediating signal transmission at synapses.
CHRFAM7A is expressed in the hippocampus, and alternative splicing produces two splice variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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