Thermo Fisher Scientific TYROBP Polyclonal Antibody
TYROBP(DAP12) 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot과 Immunoprecipitation에 사용 가능하며, 1 mg/mL 농도의 액상 형태로 제공됩니다. DAP12 신호전달 연구용으로 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunoprecipitation (IP) | 2–4 µg/mL protein lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant DAP12 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2304045 |
Product Specific Information
A suggested positive control for this product is NKp44 positive cells.
Target Information
DAP12 (also known as TYROBP) is a transmembrane adaptor protein associated with several cell surface receptors on natural killer (NK), myeloid, and neuronal cells. It contains an ITAM domain that recruits the protein tyrosine kinase Syk to initiate signal transduction.
Deficiency of DAP12 leads to impaired antigen presentation by myeloid cells and defective NK receptor function in mice, as well as presenile dementia and bone cysts in humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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