Thermo Fisher Scientific EDG3 Polyclonal Antibody
EDG3 단백질(C-terminal)에 특이적인 Rabbit Polyclonal Antibody로, Western blot 등 연구용에 적합. Human 시료 반응성, 비결합형 액상 형태로 제공. PBS 버퍼에 sodium azide 포함, -20°C 보관 권장.
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- PA112702
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- pk
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Thermo Fisher Scientific EDG3 Polyclonal Antibody
Applications
- Western Blot (WB): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the C-terminal of EDG3 (S1P3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1074139 |
Product Specific Information
A suggested positive control for this product is RH7777 cells transfected with EDG3 protein.
Target Information
EDG-3 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-3 is sphingosine-1-phosphate. There are eight known members of the EDG receptor family, implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions dependent on cytoskeletal responses such as contraction, secretion, adhesion, and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG-3 is expressed in cardiovascular, leukocyte-containing, and other tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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