Thermo Fisher Scientific CHMP2B Polyclonal Antibody
CHMP2B 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. WB 및 IHC에 사용 가능하며 인간, 마우스, 랫트 반응성. 동결건조 형태로 제공되며 4°C 또는 -20°C 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal of human CHMP2B conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: CHMP2B.
Target Information
CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein.
It is widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta, and leukocytes.
CHMP2B associates directly with CHMP2A and VPS4 for the disassembly of the ESCRT-III complex.
Defects in the CHMP2B gene are associated with chromosome 3-linked frontotemporal dementia (FTD3).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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