Thermo Fisher Scientific ABO Recombinant Rabbit Monoclonal Antibody (ARC1251)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC1251

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BGAT (P16442) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ABO,uniProtId:P16442-1,ncbiNodeId:9606,antigenRange:1-100,antigenLength:354,antigenImageFileName:MA5-35675_ABO_P16442-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35675_ABO_P16442-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.47 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849575

Product Specific Information

Immunogen sequence: MAEVLRTLAG KPKCHALRPM ILFLIMLVLV LFGYGVLSPR SLMPGSLERG FCMAVREPDH LQRVSLPRMV YPQPKVLTPC RKDVLVVTPW LAPIVWEGTF

Target Information

Histo-blood group ABO system transferase (NAGAT) is a member of the glycosyltransferase 6 family of proteins and the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B and H; the NAGAT protein functions as the basis of this group. A, B and AB individuals express a glycosyltransferase activity converting the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), while O individuals do not express this glycosyltransferase activity. The B phenotype of NAGAT differs from the A form by a few residue substitutions, whereas the O form is a result of a single base frame-shift deletion in the N-terminal extremity of the gene. The NAGAT protein localizes to the Golgi apparatus and its conserved DXD motif functions in cofactor binding.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.