
Thermo Fisher Scientific ABO Recombinant Rabbit Monoclonal Antibody (ARC1251)
ABO 혈액형 관련 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간 시료 반응성이 있으며 HEK293 세포에서 발현된 IgG 형식입니다. 고순도 친화 크로마토그래피 정제, 안정적인 액상 형태로 연구용에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1251 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human BGAT (P16442) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.47 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849575 |
Product Specific Information
Immunogen sequence:
MAEVLRTLAG KPKCHALRPM ILFLIMLVLV LFGYGVLSPR SLMPGSLERG FCMAVREPDH LQRVSLPRMV YPQPKVLTPC RKDVLVVTPW LAPIVWEGTF
Target Information
Histo-blood group ABO system transferase (NAGAT) is a member of the glycosyltransferase 6 family and forms the basis of the ABO blood group system. The ABO system involves three carbohydrate antigens: A, B, and H.
NAGAT converts the H antigen to A (via UDP-GalNAc) or B (via UDP-Gal), while O individuals lack this activity.
The B phenotype differs from A by a few residue substitutions, and the O form results from a frame-shift deletion.
NAGAT localizes to the Golgi apparatus and its conserved DXD motif functions in cofactor binding.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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