Thermo Fisher Scientific DP1 Recombinant Rabbit Monoclonal Antibody (ARC1202)
Recombinant rabbit monoclonal antibody against human DP1/TFDP1. Validated for WB, IHC(P), and ELISA. High specificity and reproducibility using HEK293 expression system. Supplied in liquid form with 50% glycerol for stable long-term storage.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1202 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 311–410 of human DP1/TFDP1 (Q14186) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.35 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849576 |
Product Specific Information
Immunogen sequence:
SGSCSAEDLK MARSLVPKAL EPYVTEMAQG TVGGVFITTA GSTSNGTRFS ASDLTNGADG MLATSSNGSQ YSGSRVETPV SYVGEDDEED DDFNENDEDD
Target Information
The DP family contains at least two members, DP1 and DP2. Structurally, DP1 and DP2 are relatively conserved, but their expression appears to be tissue specific. E2F1, a functional target for the tumor suppressor protein Rb, heterodimerizes with DP1 to form an active E2F transcriptional complex. The interaction between E2F and DP family members is mediated in part by a leucine repeat that is weakly conserved between the two families.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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