Thermo Fisher Scientific FKBP5/FKBP51 Polyclonal Antibody
FKBP5/FKBP51 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, IP 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공되며, 인체 반응성 확인. 연구용 전용 제품.
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Thermo Fisher Scientific FKBP5/FKBP51 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 407 and 457 of human FK506 binding protein 5 (51 kDa FK506-binding protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
FKBP5 is a member of the immunophilin protein family, involved in immunoregulation and basic cellular processes such as protein folding and trafficking.
It acts as a cis-trans prolyl isomerase binding to immunosuppressants FK506 and rapamycin, mediating calcineurin inhibition.
FKBP5 interacts with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein.
The FKBP5 gene includes multiple polyadenylation sites, and alternative splicing results in multiple transcript variants.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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