Thermo Fisher Scientific ITGB1BP3 Polyclonal Antibody
Rabbit Polyclonal Antibody targeting Human ITGB1BP3. Validated for IHC (Paraffin) with dilution range 1:200–1:500. Unconjugated, purified by antigen affinity chromatography, supplied in PBS with glycerol and sodium azide. Suitable for research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human ITGB1BP3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2664873 |
Product Specific Information
Immunogen sequence:
VYLDGMKSREE LFREVLEDIQ NSLLNRSQES APSPARPART QGPGRGCGHR TARPAASQQD SM
Highest antigen sequence identity to the following orthologs:
- Mouse: 35%
- Rat: 34%
Target Information
ITGB1BP3 catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN).
The protein reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin.
It is involved in the regulation of PXN at the protein level and PXN tyrosine phosphorylation, and may play a role in the regulation of terminal myogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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