Thermo Fisher Scientific Glutathione S-Transferase Mu3 (GSTM3) Monoclonal Antibody (CPTC-GSTMu3-1)
Thermo Fisher Scientific의 GSTM3 단일클론 항체(CPTC-GSTMu3-1)는 인간 GSTM3 단백질을 인식하며 Western blot, IHC, Peptide Array에 적합합니다. 단백질 A/G로 정제된 액상 항체로, 보존제가 없으며 -20°C 이하에서 보관합니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- 2947-MSM1-P1ABX
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CPTC-GSTMu3-1 |
| Immunogen | Recombinant full-length human GSTM3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at room temperature for 20 minutes.
Target Information
Glutathione S-transferase M3 (GSTM3) is an enzyme encoded by the GSTM3 gene in humans. It belongs to the mu class of glutathione S-transferases, which play a role in detoxification of electrophilic compounds such as carcinogens, drugs, and environmental toxins through conjugation with glutathione.
The mu class genes are organized in a cluster on chromosome 1p13.3 and are highly polymorphic, influencing susceptibility to toxins and drug efficacy. Mutations in GSTM3 have been associated with a slight increase in certain cancers due to environmental toxin exposure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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