Thermo Fisher Scientific Glutathione S-Transferase Mu3 (GSTM3) Recombinant Mouse Monoclonal Antibody (rGSTM3/8878)
Recombinant mouse monoclonal antibody targeting human GSTM3 for IHC(P) applications. High specificity and purity via Protein A/G purification. Provided as liquid form, unconjugated, suitable for cytoplasmic detection. For research use only.
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Applications
- Immunohistochemistry (Paraffin) [IHC (P)]: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rGSTM3/8878 |
| Immunogen | Recombinant full-length human GSTM3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Brain, HeLa cell lysate, human liver, testis, or kidney
- Cellular Location: Cytoplasm
Target Information
Glutathione S-transferase M3 (GSTM3) is an enzyme encoded by the GSTM3 gene. It belongs to the mu class of glutathione S-transferases involved in detoxification of electrophilic compounds such as carcinogens, therapeutic drugs, and oxidative stress products through conjugation with glutathione.
The mu class genes are located on chromosome 1p13.3 and exhibit high polymorphism, influencing individual susceptibility to toxins and drug efficacy. Mutations in this gene have been associated with increased cancer risk due to environmental toxin exposure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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