Thermo Fisher Scientific SNRPA1 Polyclonal Antibody
SNRPA1 단백질을 표적하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, IP 등 다양한 응용에 적합. 액상 형태로 1 mg/mL 농도, 4°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Item | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 205–255 of Human Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA1, UniProt ID: P09661-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
- Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
SNRPA1 (U2 snRNP-A) is located on gene map locus 15q26.3 and encodes a 28 kDa protein that is a specific component of the U2 snRNP particle. It includes a unique N-terminal leucine-rich region and a hydrophobic RNA-binding C-terminal region.
Unlike other RNA-binding proteins, SNRPA1 lacks segments homologous to RNP1 and RNP2 motifs. It associates with U2 snRNP and participates in transcription and pre-mRNA splicing, potentially playing a role in cell division and proliferation.
Autoantibodies against snRNP particles are often found in patients with connective tissue disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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