Thermo Fisher Scientific SNRPA1 Polyclonal Antibody
SNRPA1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 4°C에서 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 205–255 of Human Small Nuclear Ribonucleoprotein Polypeptide A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC: Epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
Target Information
SNRPA1 (U2 snRNP-A) is located at gene locus 15q26.3 and encodes a 28 kDa protein, a specific component of the U2 snRNP particle. It has a unique N-terminal leucine-rich region and a hydrophobic RNA-binding C-terminal region, lacking RNP1 and RNP2 motifs found in other RNA-binding proteins. SNRPA1 associates with U2 snRNP and is involved in transcription and pre-mRNA splicing. It may play a role in cell division and proliferation. Autoantibodies against snRNP particles are often found in patients with connective tissue disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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