Thermo Fisher Scientific LRBA Polyclonal Antibody
인간 LRBA 단백질에 특이적인 Rabbit Polyclonal 항체로, IHC(P)에서 1:1,000~1:2,500 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS, 40% 글리세롤 완충액에 보관. 연구용으로만 사용.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human LRBA. Recombinant protein control fragment (Product # RP-92443) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2643454 |
Product Specific Information
Immunogen sequence:
GGWRVWVDTL SITHSKVTFE IHKENLANIF REQQGKVDEE IGLCSSTSVQ AASGIRRDIN VSVGSQQPDT KDSPVCPHFT TNGNENSSIE KTSSLESASN IELQTTNTSY EEMKAEQENQ ELPDEGTLEE TL
- Highest antigen sequence identity to orthologs:
- Mouse: 67%
- Rat: 65%
Target Information
The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, aiding in the secretion and/or membrane deposition of immune effector molecules.
Defects in this gene are associated with common variable immunodeficiency-8 with autoimmunity.
Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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