Thermo Fisher Scientific GREM2 Polyclonal Antibody

Applications and Tested Dilution

Western Blot (WB)

• Tested Dilution: 0.1 µg/mL

ELISA

• Tested Dilution: 0.1–0.4 µg/mL (Detection), 0.2–0.8 µg/mL (Capture)

Product Specifications

Product Specific Information

In sandwich ELISAs, less than 0.1% cross-reactivity with recombinant mouse (rm) Cerberus, rmGremlin, rmDAN, recombinant human (rh) COCO, rhGremlin, and rmBMP-4 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.

Target Information

GREM2 encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers.
The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring.
The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins.
As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지: PA5-47247_GREM2_O88273-1_Goat.svg)
(이미지: PA5-47247_GREM2_O88273-1_Goat_PDP.jpeg)