
Thermo Fisher Scientific GREM2 Polyclonal Antibody
Thermo Fisher Scientific의 GREM2 Polyclonal Antibody는 Mouse GREM2 단백질을 인식하는 Goat 유래 IgG 항체로, WB 및 ELISA에 사용됩니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, PBS+trehalose 버퍼에 동결건조 형태로 제공됩니다.
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Applications and Tested Dilution
Western Blot (WB)
- Tested Dilution: 0.1 µg/mL
ELISA
- Tested Dilution: 0.1–0.4 µg/mL (Detection), 0.2–0.8 µg/mL (Capture)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant mouse PRDC Arg22–Gln168 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609989 |
Product Specific Information
In sandwich ELISAs, less than 0.1% cross-reactivity with recombinant mouse (rm) Cerberus, rmGremlin, rmDAN, recombinant human (rh) COCO, rhGremlin, and rmBMP-4 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
GREM2 encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers.
The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring.
The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins.
As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-47247_GREM2_O88273-1_Goat.svg)
(이미지: PA5-47247_GREM2_O88273-1_Goat_PDP.jpeg)
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