Thermo Fisher Scientific SEMA7A Polyclonal Antibody
인간 SEMA7A 단백질을 인식하는 Thermo Fisher Scientific의 Polyclonal 항체입니다. Western blot 및 유세포분석에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 보존제 무첨가, 동결건조 형태로 제공되어 연구용으로 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg per million cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Semaphorin 7A (His47–Ala648) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2610075 |
Product Specific Information
- In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse Semaphorin 7A is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
CD108 (Sema7A) is a GPI-anchored semaphorin family member that enhances central and peripheral axonal growth and is required for proper axon track formation during embryogenesis.
CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in the immune system affects cell proliferation, chemotaxis, and cytokine release.
On erythrocytes, CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signals through its receptors, plexin C1 and beta1 integrins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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