ELK Biotechnology CBP 35 rabbit pAb
Galectin-3 단백질을 인식하는 토끼 다클론 항체로, WB, IHC, IF, ELISA에 적합합니다. 인간, 생쥐, 랫드 시료에 반응하며 세포질, 핵, 분비 경로에서 발현되는 단백질 검출에 유용합니다. -20°C에서 1년간 보관 가능합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology CBP 35 rabbit pAb
ELK Biotechnology CBP 35 rabbit pAb
제품 개요
Galectin-3 (CBP 35)는 β-galactoside 결합 단백질로, 세포질, 핵, 세포외 기질 등 다양한 위치에서 발현되며 세포사멸, 면역반응, 세포 부착 및 T세포 조절 등에 관여합니다. 본 항체는 인간 Galectin-3 유래 합성 펩타이드를 면역원으로 제작된 토끼 다클론 항체입니다.
제품 사양
| 항목 | 내용 |
|---|---|
| Product name | CBP 35 rabbit pAb |
| Alternative Names | LGALS3; MAC2; Galectin-3; Gal-3; 35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; IgE-binding protein; L-31; Laminin-binding protein; Lectin L-29; Mac-2 antigen |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Galectin-3 (AA range: 141–190) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 33 kDa |
| Gene ID (Human) | 3958 |
| Human Swiss-Prot No. | P17931 |
| Cellular Localization | Cytoplasm, Nucleus, Secreted (non-classical pathway). Secreted via TMED10-mediated translocation through ERGIC and vesicle secretion (PubMed:32272059). |
| Species Reactivity | Human, Mouse, Rat |
Background
This gene encodes a member of the galectin family of carbohydrate-binding proteins with affinity for β-galactosides. The protein contains an N-terminal proline-rich tandem repeat domain and a C-terminal carbohydrate recognition domain. It can self-associate via the N-terminal domain to bind multivalent saccharide ligands. Galectin-3 is localized in the extracellular matrix, cytoplasm, and nucleus, and participates in apoptosis, innate immunity, cell adhesion, and T-cell regulation. It also exhibits antimicrobial activity against bacteria and fungi. Alternative splicing leads to multiple transcript variants. (RefSeq, Oct 2014)
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.