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ELK Biotechnology Tau (phospho Ser396) rabbit pAb
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Tau 단백질의 Ser396 인산화 부위를 인식하는 rabbit polyclonal antibody로, IF, WB, IHC, ELISA에 사용 가능. 인간, 마우스, 랫트 시료에 반응하며, 알츠하이머 등 신경퇴행성 질환 연구에 적합. -20°C에서 1년 보관 가능.
- 판매단위
- pk
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ELK Biotechnology ES1412-100UL Tau (phospho Ser396) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES1412-50UL Tau (phospho Ser396) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology Tau (phospho Ser396) rabbit pAb
Tau (phospho Ser396) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Tau (phospho Ser396) rabbit pAb |
| Alternative Names | MAPT; MAPTL; MTBT1; TAU; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau |
| Applications | IF; WB; IHC; ELISA |
| Recommended Dilutions | IF: 1:50–200; WB: 1:500–2000; IHC: 1:50–300 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Tau around the phosphorylation site of Ser396. AA range: 681–730 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 50–85 kDa |
| Gene ID (Human) | 4137 |
| Human Swiss-Prot No. | P10636 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Cytoplasm, cytosol; Cell membrane (peripheral membrane protein, cytoplasmic side); Cytoskeleton; Axon; Dendrite; Secreted. Mostly found in neuronal axons, cytosol, and associated with plasma membrane components (PubMed:10747907). Can be secreted via TMED10-mediated pathway involving ERGIC and vesicular transport (PubMed:32272059). |
Background
This gene encodes the microtubule-associated protein tau (MAPT), which undergoes complex, regulated alternative splicing, generating several mRNA species. MAPT transcripts are differentially expressed in the nervous system depending on neuronal maturation stage and type. Mutations in the MAPT gene are associated with neurodegenerative disorders including Alzheimer’s disease, Pick’s disease, frontotemporal dementia, corticobasal degeneration, and progressive supranuclear palsy.
[provided by RefSeq, Jul 2008]
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