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ELK Biotechnology Cables1 rabbit pAb
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Cables1 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간 및 생쥐 시료에 반응하며 세포주기 조절 연구에 적합. -20°C 보관 시 1년 안정적. 농도 1 mg/ml, 핵 및 세포질에 발현되는 단백질 검출에 유용.
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ELK Biotechnology ES1820-100UL Cables1 rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES1820-50UL Cables1 rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology Cables1 rabbit pAb
Cables1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Cables1 rabbit pAb |
| Alternative Names | CABLES1; CABLES; CDK5 and ABL1 enzyme substrate 1; Interactor with CDK3 1; Ik3-1 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Ik3-1 (AA range: 561–610) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 67 kD |
| Gene ID (Human) | 91768 |
| Human Swiss-Prot No | Q8TDN4 |
| Cellular Localization | Nucleus, Cytoplasm. Located in the cell body and proximal region of the developing axonal shaft of immature neurons. Located in axonal growth cone, but not in the distal part of the axon shaft or in dendritic growth cone of mature neurons (By similarity). |
| Species Reactivity | Human; Mouse |
Background
This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
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