ELK Biotechnology AKAP 95 rabbit pAb

AKAP 95 rabbit pAb

제품 개요

• 공급업체: ELK Biotechnology
• 제품명: AKAP 95 rabbit pAb
• 대체명칭: AKAP8; AKAP95; A-kinase anchor protein 8; AKAP-8; A-kinase anchor protein 95 kDa; AKAP 95

응용 분야

• Applications: WB, IHC, IF, ELISA
• Recommended Dilutions:
  • Western Blot: 1/500 – 1/2000
  • Immunohistochemistry: 1/100 – 1/300
  • Immunofluorescence: 1/200 – 1/1000
  • ELISA: 1/20000
  • Not yet tested in other applications

제품 사양

세포 내 위치

Nucleus, Nucleus matrix, Nucleus nucleolus, Cytoplasm. Associated with the nuclear matrix in interphase and redistributes mostly to chromatin at mitosis. Upon nuclear reassembly at the end of mitosis, is sequestered into the daughter nuclei where it re-acquires an interphase distribution. Exhibits partial localization to the nucleolus in interphase, colocalizing with UBTF/UBF. Also colocalizes with GJA1 at the nuclear membrane during cell cycle G1/S phase.

배경 정보

This gene encodes a member of the A-kinase anchor protein family. These scaffold proteins contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. The encoded nuclear A-kinase anchor protein binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011]