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ELK Biotechnology Lyn (phospho Tyr508) rabbit pAb
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ELK Biotechnology Lyn (phospho Tyr508) rabbit pAb

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Lyn 단백질의 Tyr508 인산화 부위를 인식하는 rabbit polyclonal antibody로, WB, IHC, IF, ELISA 등에 사용 가능. 인간, 마우스, 랫트 반응성. 세포막, 핵, 세포질 등 다양한 세포 위치에서 Lyn 단백질 검출에 적합.

판매단위
pk
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ELK Biotechnology ES1474-100UL Lyn (phospho Tyr508) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES1474-50UL Lyn (phospho Tyr508) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology Lyn (phospho Tyr508) rabbit pAb

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Lyn (phospho Tyr508) rabbit pAb

제품 정보

항목 내용
Alternative Names LYN; JTK8; Tyrosine-protein kinase Lyn; Lck/Yes-related novel protein tyrosine kinase; V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; p53Lyn; p56Lyn
Applications WB; IHC; IF; ELISA
Recommended Dilutions Western Blot: 1/500 - 1/2000
Immunohistochemistry: 1/100 - 1/300
ELISA: 1/10000
Not yet tested in other applications
Immunogen Synthesized peptide derived from human Lyn around the phosphorylation site of Tyr507 (AA range: 463-512)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 53, 56 kD
Gene ID (Human) 4067
Human Swiss-Prot No. P07948
Species Reactivity Human; Mouse; Rat
Cellular Localization Cell membrane, nucleus, cytoplasm, perinuclear region, Golgi apparatus. Detected on plasma membrane lipid rafts. Accumulates in the nucleus by inhibition of CRM1-mediated nuclear export. Nuclear accumulation increases when kinase activity is inhibited. Trafficking from Golgi to plasma membrane is kinase domain-dependent but activity-independent and mediated by exocytic vesicular transport.
Background This gene encodes a tyrosine protein kinase involved in the regulation of mast cell degranulation and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. (RefSeq, Jul 2011)

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