ELK Biotechnology Histone H3 (Acetyl Lys27) rabbit pAb
Histone H3 (Acetyl Lys27) rabbit polyclonal antibody for WB, IHC, IF, IP, and ELISA applications. Recognizes acetylated Lys27 of human Histone H3. High specificity and sensitivity for nuclear/chromosomal localization studies. Suitable for multiple spec...
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Histone H3 (Acetyl Lys27) rabbit pAb
제품 개요
Histone H3 (Acetyl Lys27) rabbit polyclonal antibody는 인간 Histone H3의 Lys27 아세틸화 부위를 인식하도록 제작된 항체로, 다양한 면역학적 분석에 사용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H3 (Acetyl Lys27) rabbit pAb |
| Alternative Names | HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; H3FH; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3; H3k27AC |
| Applications | WB; IHC; IF; IP; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 IP: 1/200 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Histone H3 around acetylated Lys27 (AA range: 11–60) |
| Host Species | Rabbit |
| Storage | -20°C (1 year) |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 17 kDa |
| GeneID (Human) | 8350, 8351, 8352, 8353, 8354, 8355, 8356, 8357, 8358, 8968, 126961, 333932, 653604, 3020, 3021 |
| Human Swiss-Prot No | P68431, Q71DI3, P84243 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat, Monkey, Arabidopsis thaliana |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Each nucleosome consists of approximately 146 bp of DNA wrapped around an octamer composed of pairs of four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted via interaction with linker histone H1, forming higher-order chromatin structures. This gene is intronless and encodes a replication-dependent histone H3 family member. Transcripts lack polyA tails and instead contain a palindromic termination element. Located within the large histone gene cluster on chromosome 6p22–p21.3. (RefSeq, Aug 2015)
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