ELK Biotechnology HDAC2 (phospho Ser394) rabbit pAb
HDAC2 (phospho Ser394) rabbit polyclonal antibody로, 인산화된 Ser394 부위 인식. WB 및 ELISA에 적합하며, 핵과 세포질에서 발현되는 HDAC2 단백질 검출에 사용. 고순도 IgG, 1 mg/ml 농도, -20°C 보관 안정성 우수.
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제품명
HDAC2 (phospho Ser394) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | HDAC2; Histone deacetylase 2; HD2 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human HDAC2 around the phosphorylation site of Ser394 (AA range: 360–409) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 55 kD |
| Gene ID (Human) | 3066 |
| Human Swiss-Prot No. | Q92769 |
| Cellular Localization | Nucleus, Cytoplasm |
| Species Reactivity | Human; Mouse; Rat; Monkey |
Background
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3, and H4).
This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor.
Thus, it plays an important role in transcriptional regulation, cell cycle progression, and developmental events.
Alternative splicing results in multiple transcript variants.
[provided by RefSeq, Apr 2010]
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