Thermo Fisher Scientific Pannexin 1 Polyclonal Antibody
Pannexin 1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot, IHC, Flow Cytometry에 사용 가능. 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 2-8°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | - |
| Immunohistochemistry (IHC) | 20 µg/mL | - |
| Flow Cytometry (Flow) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 17 amino acid peptide near the amino terminus of human PANX1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551827 |
Product Specific Information
- Suggested positive control: human ovary tissue lysate
- PA5-34475 can be used with blocking peptide PEP-1517
Target Information
The pannexin gene family encodes a second class of putative gap junction proteins and is highly conserved in invertebrates and mammals.
Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels.
Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is more distantly related.
PANX1 forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum.
It may act as a Ca²⁺-leak channel regulating ER Ca²⁺ homeostasis and neural stem/progenitor cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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