Thermo Fisher Scientific DNAJC2 Polyclonal Antibody
DNAJC2 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC 등 다양한 응용에 적합. 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며, 장기 보관 시 -20°C에서 안정적으로 저장 가능.
- 카탈로그번호
- PA554212
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DNAJC2. Recombinant protein control fragment (Product #RP-92635). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640701 |
Product Specific Information
Immunogen sequence:
EEINEQIRKE KEEAEARMRQ ASKNTEKSTG GGGNGSKNWS EDDLQLLIKA VNLFPAGTNS RWEVIANYMN IHSSSGVKRT AKDV
Sequence identity:
- Mouse: 92%
- Rat: 90%
Target Information
EIF4EBP1 is a translation repressor protein that interacts directly with eukaryotic translation initiation factor 4E (eIF4E), a limiting component of the multisubunit complex recruiting 40S ribosomal subunits to the 5' end of mRNAs. Interaction with eIF4E inhibits complex assembly and represses translation. This protein becomes phosphorylated in response to signals such as UV irradiation and insulin signaling, leading to dissociation from eIF4E and activation of mRNA translation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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