Thermo Fisher Scientific KIAA0391 Polyclonal Antibody
Human KIAA0391 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 버퍼에 보관. 미토콘드리아 tRNA 성숙 관련 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human KIAA0391 (Product #RP-89039) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643004 |
Product Specific Information
Immunogen sequence:
SYVSLFLADR CGIRNQQRLF SLKTMSPQNT KATNLIAKAR YLRKDEGSNK QVYSVPHFFL AGAAKERSQM NSQTEDHALA PVRNTIQLPT QPLNSEEWDK LKEDLKENTG KTSFESWIIS QMAGCHSSID VAKSLLAW
- Highest antigen sequence identity to the following orthologs:
- Mouse: 57%
- Rat: 58%
Target Information
KIAA0391, also known as MRPP3 (mitochondrial ribonuclease P protein 3), is a 583 amino acid protein located in the mitochondria.
It functions in tRNA maturation and is a component of mitochondrial ribonuclease P, which cleaves tRNA at the 5'-end.
Mitochondrial ribonuclease P consists of RG9MTD1, MRPP22, and KIAA0391 subunits.
Due to alternative splicing, KIAA0391 exists as four isoforms.
The gene encoding KIAA0391 maps to human chromosome 14, which contains about 700 genes and makes up about 3.5% of human cellular DNA.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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