Thermo Fisher Scientific GCAT Polyclonal Antibody
Thermo Fisher Scientific의 GCAT Polyclonal Antibody는 인간 GCAT 단백질을 인식하는 토끼 유래 IgG 항체로, IHC 및 ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 안정적인 PBS-글리세롤 버퍼에 보관됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GCAT. Recombinant protein control fragment (Product #RP-91481) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641905 |
Product Specific Information
Immunogen sequence:
CLASRYGALV FMDECHATGF LGPTGRGTDE LLGVMDQVTI INSTLGKALG GASGGYTTGP GPLVSLLRQR ARPYLFSNSL PPAVVGCASK ALDLLMGSNT IVQSMAAKTQ RFRSKMEAAG FTISGA
Highest antigen sequence identity to the following orthologs:
- Mouse: 91%
- Rat: 92%
Target Information
The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase.
GCAT is the second enzyme in this pathway, catalyzing the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA.
This enzyme is a class II pyridoxal-phosphate-dependent aminotransferase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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